Personal characteristics, degree of satisfaction for work, subjective symptoms, and stress related to working condition were investigated from 150 workers exposed to organinc solvents in shoe factories and 53 official workers in Pusan area, and
urinary
hippuric acid concentration which represented the amount of exposed organic solvents, BUN and serum creatinine which were renal function tests for worker's health examination and urinary N-acetyl-β-D-glucosaminidase activity were measured. @ES
The
results obtained were summarized as follows.
@EN 1. The mean value of urinary NAG activity of exposed group was higher than that of control group (p<0.01) and subjects whose NAG activities were over refrence range in exposed group were far more than in control group (p<0.05), therefore
urinary NAG
activity was a sensitive test for the change of renal function due to exposure of organic solvents.
2. Unsatisfaction for occupation, want to change occupation, worry about health, stress related to job and symptoms releated to exposure of organic solvents investigated by questionnaire were higher in exposed group than in control group,
therefore
the
health management for workers exposed to organic solvents in shoe factories was important in the viewpoint of occupational medicine.
3. The mean value of urinary NAG activity in the subjects whose working duration were over 5 years was higher than in the subjects whose working duration were over 5 years was higher than in the subjects whose working duration were under 5 years,
therefore the longer exposured duration was the higher urinary NAG activity was.
4. Urinary NAG activity had positive correlation with time weighted amount of total toluene exposure therefore dose-response relationship was suspected.
As above results, it will be very usful to apply the data of urinary NAG activity to the health management of workers exposed to orgaic solvents in order to monitoring of early renal dysfunction which was common in the workers chornically to
mixed
organic solvents.
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